Mouse myeloma cell line NS0-derived recombinant mouse MFG-E8. Ala23-Cys463 Accession Number P21956
Conjugate
Unconjugated
Applications
Application Notes
Western Blot 1 μg/mL; LISA Capture 2-8 μg/mL ELISA Detection 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4064 - DPABY-642
MFG-E8, originally identified as a product of lactating mammary glands, is also secreted by activated macrophages and immature dendritic cells. MFG-E8 functions as an opsonin by binding phosphatidylserine on apoptotic cells and enhancing their phagocytosis.
Pathway
Amyloids; Disease;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Ruggiero, L; Connor, MP; et al. Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5(-/-) or Mfge8(-/-) mouse retina. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:8145-8148(2012).
Watanabe, T; Totsuka, R; et al. Production of the long and short forms of MFG-E8 by epidermal keratinocytes. CELL AND TISSUE RESEARCH 321:185-193(2005).
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COA
Certificate of Analysis
