A synthetic peptide of human METTL11A is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
METTL11A; methyltransferase like 11A; C9orf32, chromosome 9 open reading frame 32; alpha N-terminal protein methyltransferase 1A; AD 003; N-terminal RCC1 methyltransferase; methyltransferase-like protein 11A; X-Pro-Lys N-terminal protein methyltransferase
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation.
Citations
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