Synthetic peptide within Human CRSP2/ MED14 aa 585-615 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: O60244
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500;
Target
Alternative Names
MED14; mediator complex subunit 14; CSRP; RGR1; CRSP2; EXLM1; CXorf4; CRSP150; DRIP150; TRAP170; mediator of RNA polymerase II transcription subunit 14; hRGR1; ARC150; RGR1 homolog; CRSP complex subunit 2; human homolog of yeast RGR1; transcriptional co-a
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
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