Anti-MAP4K2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human MAP4K2 is used for rabbit immunization.

Conjugate

Alternative Names

MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2; RAB8IP; BL44; GCK; MEKKK 2; GC kinase; MEK kinase kinase 2; germinal center kinase; Rab8 interacting protein; rab8-interacting protein; MAPK/ERK kinase kinase kinase 2; germinal centre kinas

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Pathway

Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; TNF receptor signaling pathway, organism-specific biosystem;