Synthetic peptide within Human Germinal Center Kinase aa 320-349 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q12851
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500; Flow Cyt: 1/10 - 1/50;
Target
Alternative Names
MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2; GCK; BL44; RAB8IP; MEKKK 2; MEK kinase kinase 2; Rab8 interacting protein; MAPK/ERK kinase kinase kinase 2; germinal centre kinase (GC kinase); B lymphocyte serine/threonine protein kinase;
Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.
Pathway
Insulin Signaling; MAPK signaling pathway;
Citations
Publication ()
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COA
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