Anti-MAP2K2 monoclonal antibody (DCABH-8580) Knockout Validated

Rabbit anti-Human MAP2K2 monoclonal antibody for ICC/IF, WB, IHC-P, FC, IP

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
Z89
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide corresponding to residues in N terminus of human MEK2
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/250 - 1/500; WB: 1/10000; Flow Cyt: 1/100; IP: 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MAP2K2; mitogen-activated protein kinase kinase 2; PRKMK2; dual specificity mitogen-activated protein kinase kinase 2; MEK2; MAPK/ERK kinase 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
ARMS-mediated activation, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Leich, E; Weissbach, S; et al. Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules. BLOOD CANCER JOURNAL 3:-(2013).
MacDonald, TJ; Brown, KM; et al. Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. NATURE GENETICS 29:143-152(2001).

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