Anti-MAP2K2 monoclonal antibody, clone 2B3

Name: Anti-MAP2K2 monoclonal antibody, clone 2B3
SKU: DCABH-3730

Mouse anti-Human MAP2K2 monoclonal antibody for WB, IHC-P, ICC/IF

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

2B3

Species Reactivity

Mouse; Rat; Dog; Human; African green monkey

Immunogen

Recombinant full length protein, corresponding to amino acids 1-400 of Human MEK2 produced in HEK293T cells (NP_109587).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/200 - 1/400; IHC-P: 1/150; ICC/IF: 1/100;

Target

Alternative Names

MAP2K2; mitogen-activated protein kinase kinase 2; PRKMK2; dual specificity mitogen-activated protein kinase kinase 2; MEK2; MAPK/ERK kinase 2; MAP kinase kinase 2; ERK activator kinase 2; mitogen-activated protein kinase kinase 2, p45; MKK2; MAPKK2; FLJ2

Entrez Gene ID

5605

UniProt ID

P36507

Product Background

Antigen Description

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases.

Pathway

ARMS-mediated activation, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem.

Citations