MAN2A1 (NP_002363, 1045 a.a. ~ 1144 a.a) partial recombinant protein with GST tag. The sequence is DIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKF IVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR
Conjugate
Unconjugated
Target
Alternative Names
MAN2A1; mannosidase, alpha, class 2A, member 1; MANA2; MANII; GOLIM7; AMan II; alpha-mannosidase 2; Golgi alpha-mannosidase II; mannosidase, alpha type II; golgi integral membrane protein 7; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase;
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.
Pathway
Asparagine N-linked glycosylation; N-Glycan biosynthesis; N-glycan antennae elongation in the medial/trans-Golgi; N-glycan biosynthesis, complex type
Citations
Publication ()
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