Anti-MADD monoclonal antibody (DMAB35646)

Rabbit anti-MADD monoclonal antibody for WB, IHC, ICC Datasheet

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Specifications


Host Species
Rabbit
Clone
FQS5020
Species Reactivity
N/A
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1,000 - 10,000; IHC: 1:100 - 250; ICC: 1:50 - 100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MADD; MAP-kinase activating death domain; MAP kinase-activating death domain protein; DENN; KIAA0358; RAB3GEP
Entrez Gene ID
UniProt ID
Q8WXG6

Product Background


Pathway
Caspase cascade in apoptosis, organism-specific biosystem; Ceramide signaling pathway, organism-specific biosystem; TNF receptor signaling pathway, organism-specific biosystem;

Citations


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References


Imai, A; Ishida, M; et al. MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 536:31-37(2013).
Chow, VTK; Lim, KM; et al. The human DENN gene: genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22. GENOME 41:543-552(1998).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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