Specifications
Immunogen
Synthetic peptide corresponding to residues near the C-terminus of Human Leukotriene B4 Receptor (UniProt Q15722).
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/50 - 1/100;
Target
Alternative Names
LTA4H; leukotriene A4 hydrolase; leukotriene A-4 hydrolase; LTA-4 hydrolase; FLJ17564;
Product Background
Antigen Description
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Pathway
Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; Leukotriene synthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-2438 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
