Rabbit Anti-Human LMO1 (a.a. 11-83) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human LMO1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 11-83 aa of BC069793

Conjugate

Application Notes

WB: 1:1000-1:6000

General Notes

This product (Catalog No. DPABH-29256) is a rabbit-derived polyclonal antibody raised against human LMO1, targeting the amino acid region 11–83 of the protein. This antibody exhibits cross-reactivity with Human LMO1 from mouse and rat. It has been affinity purified by Protein A. LOM1 (LIM Domain Only 1), as a Protein Coding gene, encodes a cysteine-rich, two LIM domain transcriptional regulator. It may be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL)(Uniprot). Diseases associated with LMO1 include T-Cell Acute Lymphoblastic Leukemia and Neuroblastoma (PMID:31830377). The downstream of LMO1-regulatory cascade includes a tumor-promoting LIMS1/ILK pathway, which has a potential to be a novel therapeutic target(PMID: 29695398). The molecular weight of LMO1 is 18 kDa.
DPABH-29256 is suitable for use in Western blot (WB) (1:1,000–1:6,000) application.
DPABH-29256 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Cysteine-rich protein TTG-1; LIM domain only protein 1; LMO 1; LMO-1; RBTN1

Entrez Gene ID

UniProt ID