Anti-LMO1 (aa 1-90) polyclonal antibody

Species Reactivity

Human

Immunogen

LMO1 (NP_002306, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. The sequence is MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE VGSTLYTKANLILCRRDYLRLFGTTGNCAA

Conjugate

Alternative Names

LMO1; LIM domain only 1 (rhombotin 1); TTG1; RBTN1; RHOM1; rhombotin-1; LMO-1; LIM domain only protein 1; T-cell translocation gene 1; cysteine-rich protein TTG-1; T-cell translocation protein 1;

Entrez Gene ID

UniProt ID

Antigen Description

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.