Specifications
Species Reactivity
Mouse; Human
Immunogen
Recombinant fragment: LGKCKAEHDQ LLLNYAKKES DLNGAQIKLR EYEAALNSKD AALATALGDK KSLEGDLEDL KDQIAQLEAS LAAAKKQLAD, corresponding to amino acids 107 - 186 of Human Lamin B1 (NP_005564) with a proprietary tag.
Applications
Application Notes
Flow Cyt: 0.5μg/106 cells; WB: 1 - 5 μg/ml.
Target
Alternative Names
LMNB1; lamin B1; lamin-B1; LMN; ADLD; LMN2; LMNB; MGC111419;
Product Background
Antigen Description
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Pathway
Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem;
Citations
Publication ()
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COA
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