Specifications
Species Reactivity
Mouse; Human
Immunogen
Recombinant fragment, corresponding to a region within amino acids 107-186 of Human Lamin B1 with 26 kDa proprietary tag (NP_005564).
Applications
Application Notes
WB: 1/500 - 1/1000; IHC-P: 3 μg/ml;
Target
Alternative Names
LMNB1; lamin B1; lamin-B1; LMN; ADLD; LMN2; LMNB; MGC111419;
Product Background
Antigen Description
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Pathway
Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem;
Citations
Publication ()
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COA
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