Anti-LMAN1 monoclonal antibody, clone 2C9

Antibody Isotype

IgG1

Clone

2C9

Species Reactivity

Rat; Dog; Human; Monkey

Immunogen

Recombinant full length Human LMAN1 produced in HEK293T cells (NP_005561).

Conjugate

Application Notes

WB: 1/200 - 1/500;

Alternative Names

LMAN1; lectin, mannose-binding, 1; coagulation factor V factor VIII combined deficiency , F5F8D; protein ERGIC-53; endoplasmic reticulum golgi intermediate compartment protein 53; ERGIC 53; ERGIC53; FMFD1; gp58; MCFD1; MR60; intracellular mannose specific

Entrez Gene ID

UniProt ID

Antigen Description

Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.

Pathway

Asparagine N-linked glycosylation, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Signaling events mediated by TCPTP, organism-specific biosystem; Transport to the Golgi and subsequent modification, organism-specific biosystem;