Anti-LMAN1 Polyclonal Antibody (CABT-L2217) Knockout Validated

Rabbit Anti-Human LMAN1 (Pro198~Cys475) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human LMAN1 (Pro198~Cys475)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hela cell lysate. Lane 2: LMAN1 knockout Hela cell lysate. Predicted MW: 58kd, Observed MW: 58kd
Western Blot. Sample. Human 293T cell lysate.
Western Blot. Sample. Human Hela cell lysate.
Western Blot. Sample. Human HepG2 cell lysate.

Target


Alternative Names
F5F8D; FMFD1; MCFD1; MR60; Gp58; Protein ERGIC-53
Entrez Gene ID
UniProt ID

Product Background


Pathway
Asparagine N-linked glycosylation; Defective ALG1 causes ALG1-CDG (CDG-1k); Defective ALG11 causes ALG11-CDG (CDG-1p); Defective ALG12 causes ALG12-CDG (CDG-1g); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS); Defective ALG2 causes ALG2-CDG (CDG-1i); Defective ALG3 causes ALG3-CDG (CDG-1d); Defective ALG6 causes ALG6-CDG (CDG-1c);

Citations


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References


Yamada, T; Fujimori, Y; et al. A novel missense mutation causing abnormal LMAN1 in a Japanese patient with combined deficiency of factor V and factor VIII. AMERICAN JOURNAL OF HEMATOLOGY 84:738-742(2009).

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