Recombinant fragment: cytoplasmic domain, amino acids 91-244 of human NTAL.
Conjugate
PE
Applications
Application Notes
Flow Cyt: 1/30.
Target
Alternative Names
LAT2; linker for activation of T cells family, member 2; WBSCR5, WBSCR15, Williams Beuren syndrome chromosome region 5; linker for activation of T-cells family member 2; HSPC046; LAB; linker for activation of B cells; linker for activation of T cells; tr
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem;
Citations
Publication ()
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COA
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