Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 106-135 of Human NTAL (NP_054865.2, NP_115852.1).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500.
Target
Alternative Names
LAT2; linker for activation of T cells family, member 2; LAB; NTAL; WSCR5; WBSCR5; HSPC046; WBSCR15; linker for activation of T-cells family member 2; non-T-cell activation linker; linker for activation of B-cells; membrane-associated adapter molecule; Wi
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Pathway
B Cell Receptor Signaling Pathway; Fc-epsilon receptor I signaling in mast cells; Innate Immune System;
Citations
Publication ()
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COA
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