Anti-KRT10 monoclonal antibody, clone EF-L21

Antibody Isotype

IgG1

Clone

EF-L21

Species Reactivity

Human

Immunogen

Cytoskeletal preparation extracted from human ectocervical epithelium.

Conjugate

Alternative Names

KRT10; keratin 10; keratosis palmaris et plantaris , KPP; keratin, type I cytoskeletal 10; CK10; cytokeratin 10; epidermolytic hyperkeratosis; K10; CK-10; keratin-10; BIE; EHK; KPP; BCIE;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.

Pathway

Staphylococcus aureus infection, organism-specific biosystem; Staphylococcus aureus infection, conserved biosystem;