Anti-KRT10 monoclonal antibody, clone MI3

Antibody Isotype

IgG1

Clone

MI3

Species Reactivity

Human; Mouse

Immunogen

Skin extract of a human Psoriasis patient.

Conjugate

Application Notes

Flow Cytometry (0.5-1 ug/million cells);
Immunofluorescence (0.5-1 μg/mL);
Immunohistochemistry (0.5-1 μg/mL for 30 min at RT);
Immunoprecipitation (0.5-1 ug/500 ug protein lysate);
WB (0.25-0.5 μg/mL) & The optimal working dilution should be determined by the end user.

Alternative Names

KRT10; keratin 10; keratosis palmaris et plantaris , KPP; keratin, type I cytoskeletal 10; CK10; cytokeratin 10; epidermolytic hyperkeratosis; K10; CK-10; keratin-10; BIE; EHK; KPP; BCIE;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.

Pathway

Staphylococcus aureus infection, organism-specific biosystem; Staphylococcus aureus infection, conserved biosystem;