Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human KIR2DL2 aa 300 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P43627
Applications
Application Notes
Flow Cyt: 1/10 - 1/100; WB: 1/1000 - 1/5000.
Target
Alternative Names
KIR2DL2; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2; killer cell immunoglobulin-like receptor 2DL2; CD158B1; CD158k; cl 43; nkat6; NKAT-6; p58 NK receptor CL-43; MHC class I NK cell receptor; CD158 antigen-like family
Product Background
Antigen Description
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Graft-versus-host disease, organism-specific biosystem; Graft-versus-host disease, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem.
Citations
Publication ()
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COA
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