Full length protein corresponding to Human KCNMB4 aa 1-210.Sequence: MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQAT EANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALL HSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYF NQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVV
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
KCNMB4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; calcium-activated potassium channel subunit beta-4; hbeta4; BKbeta4; slo-beta-4; k(VCA)beta-4; BK channel subunit beta-4; maxi K channel subunit beta-4; charybdotox
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
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