Specifications
Immunogen
A synthetic peptide of human KCNJ3 is used for rabbit immunization.
Target
Alternative Names
KCNJ3; potassium inwardly-rectifying channel, subfamily J, member 3; G protein-activated inward rectifier potassium channel 1; GIRK1; KGA; Kir3.1; GIRK-1; inward rectifier K+ channel KIR3.1; inward rectifier K(+) channel Kir3.1; potassium channel, inwardl
Product Background
Antigen Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
Pathway
Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; G Protein Signaling Pathways, organism-specific biosystem;
Citations
Publication ()
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