Specifications
Immunogen
A synthetic peptide of human KCNH6 is used for rabbit immunization.
Target
Alternative Names
KCNH6; potassium voltage-gated channel, subfamily H (eag-related), member 6; potassium voltage-gated channel subfamily H member 6; erg2; HERG2; Kv11.2; ERG-2; hERG-2; eag related protein 2; eag-related protein 2; eag-related gene member 2; ether-a-go-go-r
Product Background
Antigen Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Pathway
Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Citations
Publication ()
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