Rabbit Anti-Human ITGB7 (N-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues near the N terminal of human integrin, beta 7

Conjugate

Application Notes

WB: 1:200-1:1000
IHC: 1:50-1:200

General Notes

This product (Catalog No. DPABH-21895) is a rabbit-derived polyclonal antibody raised against human ITGB7. It has been affinity purified by Protein A. This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
DPABH-21895 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:50–1:200) applications.
DPABH-21895 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

integrin; beta 7; ITB7; ITGB7

Entrez Gene ID

UniProt ID