This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.
Pathway
Prostate cancer; Regulation of actin cytoskeleton;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-28277 in a publication? Let us know and earn a reward for your research.
Bilodeau, N; Fiset, A; et al. Proteomic Analysis of Src Family Kinases Signaling Complexes in Golgi/Endosomal Fractions Using a Site-Selective Anti-Phosphotyrosine Antibody: Identification of LRP1-Insulin Receptor Complexes. JOURNAL OF PROTEOME RESEARCH 9:708-717(2010).
CHAN, J; WATT, VM; et al. EEK AND ERK, NEW MEMBERS OF THE EPH SUBCLASS OF RECEPTOR PROTEIN-TYROSINE KINASES. ONCOGENE 6:1057-1061(1991).
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Certificate of Analysis