Specifications
Immunogen
INSRR (NP_055030, 651 a.a. ~ 760 a.a) partial recombinant protein with GST tag. The sequence is LYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQ KKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDF
Target
Alternative Names
INSRR; insulin receptor-related receptor; IRR; insulin receptor-related protein; IR-related receptor;
Product Background
Antigen Description
INSRR (insulin receptor-related receptor) is a protein-coding gene. Diseases associated with INSRR include neurofibrosarcoma, and vesicoureteral reflux, and among its related super-pathways are Ras Pathway and MAPK Signaling. GO annotations related to this gene include insulin receptor substrate binding and transmembrane receptor protein tyrosine kinase activity. An important paralog of this gene is ROR1.
Pathway
Prostate cancer; Regulation of actin cytoskeleton;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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ENRICH, C; VERGES, M; et al. FUNCTIONAL IDENTIFICATION OF 3 MAJOR PHOSPHOPROTEINS IN ENDOCYTIC FRACTIONS FROM RAT-LIVER - A COMPARATIVE IN-VIVO AND IN-VITRO STUDY. EUROPEAN JOURNAL OF BIOCHEMISTRY 231:802-808(1995).
Wellhausen, L; Saeger, W; et al. Gs alpha, protein kinase C, cathepsin D, growth factors, estrogen receptor-related protein, and p53 in prolactin cell adenomas and null cell adenomas of the pituitary. ENDOCRINE PATHOLOGY 9:135-148(1998).
COA
Certificate of Analysis