Tubulin is a heterodimer consisting of α and β-tubulin subunits. It is nearly ubiquitous among eukaryotic cells. The α and β tubulins, which are each about 55 kDa MW, are homologous but not identical. α-β tubulin heterodimer is the basic building block of microtubules. This intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis.
Pathway
Cell Cycle, Mitotic; Centrosome maturation; Chaperonin-mediated protein folding; Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding; Formation of tubulin folding intermediates by CCT/TriC; G2/M Transition; Gap junction; Loss of Nlp from mitotic centrosomes; Loss of proteins required for interphase microtubule organization from the centrosome; Metabolism of proteins; Mitotic G2-G2/M phases; Pathogenic Escherichia coli infection; Phagosome; Post-chaperonin tubulin folding pa
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