This product (Catalog No. CPBT-47956RH) is a rabbit-derived polyclonal antibody raised against human TDO2. This antibody exhibits cross-reactivity with TDO2 from mouse. It has been affinity purified by Protein A. This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. CPBT-47956RH is suitable for use in Western blot (WB) (1:500–1:2,000) application. CPBT-47956RH is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Q: What was the specific target used to produce the Anti-TDO2 (aa 2-51) polyclonal antibody?
A: The source of the Anti-TDO2 (aa 2-51) polyclonal antibody is Synthetic peptide corresponding to N terminal amino acids 2-51 (SGCPFLGNNF GYTFKKLPVE GSEEDKSQTG VNRASKGGLI YGNYLHLEKV) of human TDO2.
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