Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
A synthetic peptide from the N terminal region of Human SLC9A6 conjugated to an immunogenic carrier protein.
Applications
Application Notes
WB: 1/200 - 1/2000; IHC-P: 1/200 - 1/2000; IHC-Fr: 1/200 - 1/2000.
Target
Alternative Names
SLC9A6; solute carrier family 9 (sodium/hydrogen exchanger), member 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6; sodium/hydrogen exchanger 6; KIAA0267; NHE6; 3732426M05; 6430520C02Rik; mKIAA0267; MRSA; NHE6; RP23-105E2.4; KIAA0267; N
Product Background
Antigen Description
This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.
Pathway
Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Sodium/Proton exchangers, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem;
Citations
Publication ()
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COA
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