Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide corresponding to residues in Human LCAT.
Applications
Application Notes
ICC: 1/100 - 1/250; WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/250 - 1/500;
Target
Alternative Names
LCAT; lecithin-cholesterol acyltransferase; phosphatidylcholine-sterol acyltransferase; LCAT; LCAT_HUMAN; Lecithin cholesterol acyltransferase; Lecithin-cholesterol acyltransferase; Phosphatidylcholine sterol acyltransferase; Phosphatidylcholine-sterol ac
Product Background
Antigen Description
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Pathway
Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Statin Pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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