LCAT (AAH14781, 98 a.a. ~ 197 a.a) partial recombinant protein with GST tag. The sequence is CWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGY VRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGK
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Pathway
Glycerophospholipid metabolism; HDL-mediated lipid transport; Lipoprotein metabolism; Metabolism of lipids and lipoproteins
Citations
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