Anti-INSL3 (aa 115-131) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Rhesus monkey

Immunogen

Synthetic peptide, corresponding to C terminal amino acids 115-131 of Human INSL3, differing from the related rat and mouse sequence by three amino acids.

Conjugate

Application Notes

WB: 1 - 2 μg/ml; IHC-P: 1 - 2 μg/ml.

Alternative Names

INSL3; insulin-like 3 (Leydig cell); relaxin like factor , RLNL; insulin-like 3; MGC119818; MGC119819; RLF; INSL 3; INSL3; INSL3_HUMAN; Insulin like 3; Insulin-like 3 A chain; Ley IL; Ley-I-L; Leydig insulin like peptide; Leydig insulin-like peptide; Rela

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is an insulin like hormone produced mainly in gonadal tissues in males and females. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. It may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. The mutations in this gene may lead to, but not a frequent cause of, cryptorchidism.

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin receptor SHC signaling, organism-specific biosystem; Interleukin-2 signaling, organism-specific biosystem; Interleukin-3, 5 and GM-CSF signaling,.