Anti-HFE2 monoclonal antibody (CABT-36765MH)

Mouse anti-Human HFE2 monoclonal antibody for FC, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
Gfsz-2
Species Reactivity
Mouse, Human
Immunogen
Recombinant fragment, corresponding to amino acids 36-398 of Human Repulsive Guidance Molecule C
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HFE2; hemochromatosis type 2 (juvenile); hemojuvelin; haemojuvelin; HFE2A; HJV
Entrez Gene ID
UniProt ID

Product Background


Pathway
Axon guidance, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Netrin-1 signaling, organism-specific biosystem;

Citations


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References


Andriopoulos, B; Corradini, E; et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. NATURE GENETICS 41:482-487(2009).
Martinez, AR; Niemela, O; et al. Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin. HAEMATOLOGICA 89:1441-1445(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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