Recombinant fragment: GGCPPSQRLS RSERNRRGAI TIDTARRLCK EGLPVEDAYF HCSVFDVLIS GDPNFTVAAQ AALEDARAFL PDLEKLHLFP SD, corresponding to amino acids 93-174 of Human Repulsive Guidance Molecule C with a proprietary tag (NP_973733).
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 5 μg/ml.
Target
Alternative Names
HFE2; hemochromatosis type 2 (juvenile); hemojuvelin; haemojuvelin; HFE2A; HJV; JH; repulsive guidance molecule c; RGMC; RGM domain family member C; hemochromatosis type 2 protein; MGC23953;
Mutations in Repulsive Guidance Molecule (also known as RGM-C; HJV; hemojuvelin; Hfe2) cause juvenile hemochromatosis, a severe iron overload disease. RGM-C gene expression has been characterized in the developing mouse and found to be exclusively expressed in all striated muscle and in the myocardium.
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