Anti-FBXW7 monoclonal antibody, clone GCPY 4b0/2

Antibody Isotype

IgG1

Clone

GCPY 4b0/2

Species Reactivity

Mouse; Human

Immunogen

Synthetic peptide (Human)

Conjugate

Application Notes

WB: 1μg/ml; ICC/IF: 1/100; Flow Cyt: 1μg/10⁶ cells

Alternative Names

FBXW7; F-box and WD repeat domain containing 7; F box and WD 40 domain protein 7 (archipelago homolog, Drosophila); F-box/WD repeat-containing protein 7; AGO; archipelago homolog (Drosophila); CDC4; FBW7; FBX30; FBXW6; FLJ11071; SEL 10; SEL10; AGO; Archip

Entrez Gene ID

UniProt ID

Antigen Description

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte f

Pathway

Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem.