Anti-DSG3 monoclonal antibody (CABT-29568MH)
Mouse anti-Human DSG3 monoclonal antibody for ICC/IF, IHC-P, IP, WB
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
4H244
Species Reactivity
Human
Immunogen
Recombinant fragment (Human Desmoglein 3 extracellular domain).
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 5 μg/ml; WB: 1 - 3 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Target
Alternative Names
DSG3; desmoglein 3; desmoglein 3 (pemphigus vulgaris antigen); desmoglein-3; CDHF6; pemphigus vulgaris antigen
Entrez Gene ID
UniProt ID
Product Background
Pathway
Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;
Citations
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References
Oktarina, DAM; van der Wier, G; et al. IgG-induced clustering of desmogleins 1 and 3 in skin of patients with pemphigus fits with the desmoglein nonassembly depletion hypothesis. BRITISH JOURNAL OF DERMATOLOGY 165:552-562(2011).
Stahley, SN; Saito, M; et al. Desmosome Assembly and Disassembly Are Membrane Raft-Dependent. PLOS ONE 9:-(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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