Anti-DSG3 monoclonal antibody (CABT-29568MH)

Mouse anti-Human DSG3 monoclonal antibody for ICC/IF, IHC-P, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4H244
Species Reactivity
Human
Immunogen
Recombinant fragment (Human Desmoglein 3 extracellular domain).
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 5 μg/ml; WB: 1 - 3 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
DSG3; desmoglein 3; desmoglein 3 (pemphigus vulgaris antigen); desmoglein-3; CDHF6; pemphigus vulgaris antigen
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;

Citations


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References


Zagorodniuk, I; Weltfriend, S; et al. A comparison of anti-desmoglein antibodies and indirect immunofluorescence in the serodiagnosis of pemphigus vulgaris. INTERNATIONAL JOURNAL OF DERMATOLOGY 44:541-544(2005).
Mouquet, H; Farci, S; et al. A truncated alternative spliced isoform if human desmoglein 1 contains a specific T cell epitope binding to the pemphigus foliaceus-associated HLA class II DR beta 1*0102 molecule. JOURNAL OF IMMUNOLOGY 177:6517-6526(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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