Anti-CK-BB monoclonal antibody (DMAB2204MH)

Mouse anti-Human FGFR3 monoclonal antibody for WB, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
A027-11288
Species Reactivity
Human
Immunogen
Source: Human Brain
Conjugate
Unconjugated

Target


Alternative Names
B-CK; CKBB; CKB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. The function about CK-BB antigen include ATP binding; creatine kinase activity; nucleotide binding.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Urea cycle and metabolism of amino groups, organism-specific biosystem; creatine-phosphate biosynthesis, conserved biosystem.

Citations


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References


Arnold, H; Wienker, TF; et al. High levels of brain-type creatine kinase activity in human platelets and leukocytes: A genetic anomaly with autosomal dominant inheritance. BLOOD CELLS MOLECULES AND DISEASES 48:62-67(2012).
Paltrinieri, S; Varcasia, A; et al. Brain creatine kinase isoenzyme (CK-BB) as a possible biomarker for the diagnosis in vivo of ovine coenurosis in a naturally infected flock. SMALL RUMINANT RESEARCH 94:180-184(2010).

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