Anti-Human Cell Division Cycle 25 Homolog C (CDC25C) Antibody (DMAB5464MH)

Mouse anti-Human Cell Division Cycle 25 Homolog C (CDC25C) Monoclonal antibody [clone UD-114] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
UD-114
Immunogen
BALB/C mice were injected with purified recombinant CDC25C.
Conjugate
Unconjugated

Target


Alternative Names
CDC25C; CDC25; PPP1R60; cell division cycle 25 homolog C (S. pombe); M-phase inducer phosphatase 3 mitosis inducer CDC25 cell division cycle 25C phosphotyrosine phosphatase dual specificity phosphatase CDC25C protein phosphatase 1, regulatory subunit 60 N
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of ATR in response to replication stress; Cell Cycle Checkpoints; Cell Cycle, Mitotic; Cell cycle; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Cyclin A/B1 associated events during G2/M transition; Cyclin B2 mediated events;

Citations


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References


Dalal, SN; Schweitzer, CM; et al. Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site. MOLECULAR AND CELLULAR BIOLOGY 19:4465-4479(1999).
Liu, XJ; Guo, Y; et al. Molecular basis for G(2) arrest induced by 2 '-C-cyano-21-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. CANCER RESEARCH 65:6874-6881(2005).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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