Anti-Human CD9 Antibody (CABT-33295MH)
Mouse anti-Human CD9 Monoclonal antibody [clone NFN-72] for FC, FuncS, IHC-P, IP, WB
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Tissue / cell preparation (Human). (Pre-B line Nalm-6).
CD9; CD9 molecule; CD9 antigen (p24) , MIC3; CD9 antigen; BA2; motility related protein 1
CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem; a6b1 and a6b4 Integrin signaling, organism-specific biosystem;
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Leccia, F; Nardone, A; et al. Cytometric and biochemical characterization of human breast cancer cells reveals heterogeneous myoepithelial phenotypes. CYTOMETRY PART A 81A:960-972(2012).
Stojanovic, M; Germain, M; et al. BAP31 and its caspase cleavage product regulate cell surface expression of tetraspanins and integrin-mediated cell survival. JOURNAL OF BIOLOGICAL CHEMISTRY 280:30018-30024(2005).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.