Specifications
Immunogen
Recombinant human BMPR2 extracellular domain
Applications
Application Notes
WB: 1/100 - 1/1000; Flow Cyt: 1-2μg/106 cells; IHC-P: 1/50 - 1/200.
Target
Alternative Names
BMPR2; bone morphogenetic protein receptor, type II (serine/threonine kinase); PPH1,primary pulmonary hypertension 1; bone morphogenetic protein receptor type-2; BMPR II; BMPR3; BRK 3; T ALK; BMP type II receptor; BMP type-2 receptor; BMPR 2; BMPR 3; BMPR
Product Background
Antigen Description
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.
Pathway
ALK1 signaling events, organism-specific biosystem; ALK2 signaling events, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Sign
Citations
Publication ()
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COA
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