Anti-BMPR2 monoclonal antibody (CABT-27494MH)
Mouse anti-Human BMPR2 monoclonal antibody for FC, IHC-P, WB
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
NN0070-0B20
Species Reactivity
Human
Immunogen
Recombinant human BMPR2 extracellular domain
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/1000; Flow Cyt: 1-2μg/106 cells; IHC-P: 1/50 - 1/200.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Target
Alternative Names
BMPR2; bone morphogenetic protein receptor, type II (serine/threonine kinase); PPH1,primary pulmonary hypertension 1; bone morphogenetic protein receptor type-2; BMPR II; BMPR3
Entrez Gene ID
UniProt ID
Product Background
Pathway
ALK1 signaling events, organism-specific biosystem; ALK2 signaling events, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Sign
Citations
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References
Okada, J; Ishikawa, A; et al. Anti-BMPR2 antibody in patients with pulmonary hypertension.. ARTHRITIS AND RHEUMATISM 48:S192-S192(2003).
Morse, J; Barst, R; et al. Pulmonary hypertension in scleroderma spectrum of disease: Lack of bone morphogenetic protein receptor 2 mutations. JOURNAL OF RHEUMATOLOGY 29:2379-2381(2002).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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