Anti-Heat Shock Protein monoclonal antibody (DMABT-54831MH)

Mouse Anti-Heat Shock Protein monoclonal antibody for IHC, ELISA, IF, WB Datasheet

Bring this labeled antibody directly to your bench!

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
B740/N8I
Species Reactivity
Turkey, Amphibia, Bovine, Chicken, Human, Mouse, Rabbit, Rat
Immunogen
HSP from turkey gizzard smooth muscle
Conjugate
Unconjugated

Target


Alternative Names
Heat shock proteins

Product Background


Antigen Description
Heat shock proteins (HSP) are a class of functionally related proteins involved in the folding and unfolding of other proteins. Their expression is increased when cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated. The dramatic upregulation of the heat shock proteins is a key part of the heat shock response and is induced primarily by heat shock factor (HSF). HSPs are found in virtually all living organisms, from bacteria to humans. Heat-shock proteins are named according to their molecular weight. For example, Hsp60, Hsp70 and Hsp90 (the most widely-studied HSPs) refer to families of heat shock proteins on the order of 60, 70, and 90 kilodaltons in size, respectively. The small 8-kilodalton protein ubiquitin, which marks proteins for degradation, also has features of a heat shock protein.

Citations


Have you cited DMABT-54831MH in a publication? Let us know and earn a reward for your research.

References


Reeves, RA; Lee, A; et al. Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress. ANALYTICAL BIOCHEMISTRY 457:8-18(2014).
Ho, KY; Wang, HM; et al. Evaluation and Clinical Significance of Serum Heat Shock Protein70, 60 and 27 on Hearing Recovery in Patients With Idiopathic Unilateral Sudden Hearing Loss. JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY 8:171-178(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-Heat Shock Protein monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket