Anti-PUUV Nucleoprotein Monoclonal antibody (DMAb6849)

Mouse Anti-PUUV Nucleoprotein Monoclonal antibody for ELISA, WB Datasheet

Bring this labeled antibody directly to your bench!

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2H4/I11
Species Reactivity
PUUV
Conjugate
Unconjugated

Target


Alternative Names
Puumala virus; PUUV; Bunyaviridae; Hanta virus Puumala strain antibody; Hantaan virus Puumala strain antibody; Andes virus

Product Background


Antigen Description
Hantaviruses (family Bunyaviridae) are enveloped viruses that contain a tripartite, negative-stranded RNA genome encoding an RNA-dependent RNA polymerase (L), two integral membrane glycoproteins (G1 and G2), and a nucleocapsid (N) protein. The N protein is the most abundant viral component and the major antigen in early serological response in humans and mice. It has essential functions in viral RNA replication, encapsidation, and also in virus assembly. PUUV is a causative agent of a mild form of hemorrhagic fever with renal syndrome (nephropathia epidemica) mainly in Europe and it is transmitted by the red bank vole Clethrionomys glareolus. Puumala virus is a species of hantavirus. Humans infected with the virus may develop a haemorrhagic fever with renal syndrome (HFRS) known as nephropathia epidemica. Puumala virus HFRS is lethal in a small percentage of cases. Puumala virus is named after a municipality in Finland. The virus is found predominantly in Scandinavia and Finland, although it has also been reported elsewhere in Northern Europe and Russia. Because the bank vole (Myodes glareolus) acts as a reservoir for the virus, nephropathia epidemica cases track with the vole population in a three- to four-year cycle. Humans are infected through inhalation of dust from vole droppings.

Citations


Have you cited DMAb6849 in a publication? Let us know and earn a reward for your research.

References


Acuna, R; Cifuentes-Munoz, N; et al. Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles. JOURNAL OF VIROLOGY 88:2344-2348(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-PUUV Nucleoprotein Monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket