NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Iu, MF; Kaji, H; et al. Low-dose parathyroid hormone and estrogen reverse alkaline phosphatase activity suppressed by dexamethasone in mouse osteoblastic cells. JOURNAL OF BONE AND MINERAL METABOLISM 23:450-455(2005).
Zeitoun, K; Takayama, K; et al. Deficient 17 beta-hydroxysteroid dehydrogenase type 2 expression in endometriosis: Failure to metabolize 17 beta-estradiol. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 83:4474-4480(1998).
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