Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV) of Human HSD17B8 (NP_055049).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8; FabG (beta ketoacyl [acyl carrier protein] reductase, E coli) like (E. coli); FABGL; estradiol 17-beta-dehydrogenase 8; D6S2245E; H2 KE6; HKE6; KE6; RING2; SDR30C1; short chain dehydrogenase/reductase fam
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
Pathway
Metabolic pathways; Steroid hormone biosynthesis;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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ADAMSKI, J; HUSEN, B; et al. PURIFICATION AND PROPERTIES OF ESTRADIOL 17-BETA-DEHYDROGENASE EXTRACTED FROM CYTOPLASMIC VESICLES OF PORCINE ENDOMETRIAL CELLS. BIOCHEMICAL JOURNAL 288:375-381(1992).
MAENTAUSTA, O; MENJIVAR, M; et al. TIME-RESOLVED IMMUNOFLUOROMETRIC ASSAY OF 17-BETA-HYDROXYSTEROID DEHYDROGENASE IN PLASMA. CLINICAL CHEMISTRY 37:1412-1415(1991).
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COA
Certificate of Analysis