Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV) of Human HSD17B8 (NP_055049).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8; FabG (beta ketoacyl [acyl carrier protein] reductase, E coli) like (E. coli); FABGL; estradiol 17-beta-dehydrogenase 8; D6S2245E; H2 KE6; HKE6; KE6; RING2; SDR30C1; short chain dehydrogenase/reductase fam
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
Pathway
Metabolic pathways; Steroid hormone biosynthesis;
Citations
Publication ()
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COA
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