Specifications
Species Reactivity
Mouse; Human
Immunogen
Full length native Human proteins hnRNP M3-M4 (NP_005959.2, NP_112480.2)
Applications
Application Notes
WB: 1/2000 - 1/10000; IP: 2-5 μg/mg of lysate;
Target
Alternative Names
HNRNPM; heterogeneous nuclear ribonucleoprotein M; HNRPM, NAGR1; CEA receptor; CEAR; HNRNPM4; HNRPM4; HTGR1; hnRNA-binding protein M4; N-acetylglucosamine receptor 1; heterogenous nuclear ribonucleoprotein M4; HNRPM; NAGR1; hnRNP M; DKFZp547H118;
Product Background
Antigen Description
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
Pathway
Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem;
Citations
Publication ()
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COA
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