Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
Pathway
mRNA processing;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Steiner, G; Skriner, K; et al. Autoantibodies to the A/B proteins of the heterogeneous nuclear ribonucleoprotein complex: Novel tools for the diagnosis of rheumatic diseases. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 111:314-319(1996).
PYPE, S; SLEGERS, H; et al. TYROSINE PHOSPHORYLATION OF A M(R) 38,000 A/B-TYPE HNRNP PROTEIN SELECTIVELY MODULATES ITS RNA-BINDING. JOURNAL OF BIOLOGICAL CHEMISTRY 269:31457-31465(1994).
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COA
Certificate of Analysis