Specifications
Immunogen
Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 68-98 of Human HLA G.
Applications
Application Notes
WB: 1/100 - 1/500; IHC-P: 1/50 - 1/100; Flow Cyt: 1/10 - 1/50;
Target
Alternative Names
HLA-G; major histocompatibility complex, class I, G; MHC-G; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; b2 microglobulin; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G;
Product Background
Antigen Description
Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.
Pathway
Adaptive Immune System; Allograft rejection; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Antigen processing and presentation
Citations
Publication ()
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COA
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