A synthetic peptide corresponding to residues within an internal region of Human HEXIM1.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000.
Target
Alternative Names
HEXIM1; hexamethylene bis-acetamide inducible 1; protein HEXIM1; CLP 1; EDG1; HIS1; MAQ1; HMBA-inducible; menage a quatre 1; cardiac lineage protein 1; menage a quatre protein 1; estrogen down-regulated gene 1 protein; hexamthylene bis-acetamide inducible
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Citations
Publication ()
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