Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (internal sequence)
Applications
Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250; Flow Cyt: 1/10 - 1/100.
Target
Alternative Names
HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; HERP; KIAA0025; Mif1; SUP; MMS-inducible; methyl methan
Product Background
Antigen Description
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation.
Pathway
Activation of Genes by ATF4, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; HRD1/SEL1 ERAD complex, organism-specific biosystem; HRD1/SEL1 ERAD complex, conserved biosystem; PERK regulated gene expression, organism-specific biosystem;
Citations
Publication ()
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COA
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